Affonso O R, Santos L J, Mitidieri E
Arch Int Physiol Biochim. 1979 May;87(2):223-7. doi: 10.3109/13813457909070495.
The steady-state concentrations of glutamine, glutamate and ammonia in the kidney cells might regulate the rate of renal xanthine dehydrogenase activity. Both glutamate and glutamine were found to be effective inhibitors of the renal xanthine dehydrogenase activity in vivo. The inhibition by glutamate depends essentially on the glutaminase inhibition.
肾细胞中谷氨酰胺、谷氨酸和氨的稳态浓度可能调节肾黄嘌呤脱氢酶的活性速率。在体内，谷氨酸和谷氨酰胺均被发现是肾黄嘌呤脱氢酶活性的有效抑制剂。谷氨酸的抑制作用主要取决于谷氨酰胺酶的抑制作用。
