组胺H2受体拮抗剂西咪替丁对预防大鼠实验性应激性溃疡的作用。
Effect of cimetidine, histamine H2 receptor antagonist, in the prevention of experimental stress ulcer in the rat.
作者信息
Lauterbach H H, Mattes P
出版信息
Eur Surg Res. 1978;10(2):105-8. doi: 10.1159/000127997.
PMID:658063
Abstract
The protective effect of cimetidine on gastric mucosal lesions in the rat was investigated. Through prophylactic administration of 3x 25 7g/kh body weight for 24 just prior to the test period, the incidence rate of lesions, as well as upper gastro-intestinal haemorrhage was highly significantly reduced.
摘要
研究了西咪替丁对大鼠胃黏膜损伤的保护作用。在试验期前24小时通过预防性给予3×25mg/kg体重，损伤发生率以及上消化道出血均显著降低。
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