Seymour R A, Blair G S, Wyatt F A
Br J Oral Surg. 1983 Dec;21(4):298-303. doi: 10.1016/0007-117x(83)90018-5.
The analgesics taken by patients after oral and periodontal surgery were noted over a three day observation period. Analgesic consumption matched closely the pain experience. The efficacy of self-prescribed analgesics was extrapolated from the pain scores obtained in the first 12 hours after surgery, and overall, the apparent efficacy appears poor. However, those patients who reported taking aspirin recorded significantly less pain than those who took either paracetamol or combination analgesics. Analgesic efficacy was not related to dose, although a significant correlation was noted between the number of paracetamol tablets taken and pain severity.
在为期三天的观察期内，记录了患者口腔及牙周手术后服用的镇痛药情况。镇痛药的服用量与疼痛感受密切匹配。根据术后前12小时获得的疼痛评分推断自我开具的镇痛药的疗效，总体而言，其明显疗效似乎不佳。然而，那些报告服用阿司匹林的患者所记录的疼痛明显少于服用对乙酰氨基酚或复方镇痛药的患者。镇痛药的疗效与剂量无关，尽管服用的对乙酰氨基酚片数量与疼痛严重程度之间存在显著相关性。
