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拔牙后低功率半导体激光生物刺激的临床研究

Clinical Study of Biostimulation with Low-Power Diode Laser After Dental Extractions.

作者信息

Collado Murcia Yolanda, Lopez-Jornet Pia, Parra Perez Francisco

机构信息

Facultad de Medicina y Odontologia, Departament Oral Medicine Hospital Morales Meseguer, Clínica Odontológica Universitaria, Adv Marques de los Velez s/n, 30098 Murcia, Spain.

出版信息

Clin Pract. 2025 May 6;15(5):90. doi: 10.3390/clinpract15050090.

Abstract

The objective of the present work is to assess the efficacy of photobiomodulation (PBM) with respect to pain, inflammation, and healing after tooth extractions as compared with a sham treatment. A single-blinded, randomized clinical study conducted in a private dental clinic in Murcia, it included 124 patients who needed a tooth extraction, excluding those with medical conditions that could affect healing (such as non-controlled diabetes, immunosuppression, or hemorrhagic disorders). Group I (Experimental): extraction and PBM session with a diode laser (power: 0.5 W, energy 15 J/cm for 10-30 s at 1 mm from the tissue). Group II (Sham treatment): tooth extraction and application of inactive PBM. Pain and inflammation decreased similarly in both groups over time. Anxiety decreased in both groups without significant differences ( = 0.776; = 0.246). There was no evidence that the treatment or location of the extraction had an influence on healing. Suturing the socket increased the likelihood of good healing ( = 0.048), while long procedures reduced it ( = 0.040). PBM is a non-invasive and safe therapy. This study did not show significant differences with respect to the sham treatment. More research is needed with a standardized methodology to better assess its efficacy.

摘要

本研究的目的是评估与假治疗相比,光生物调节(PBM)在拔牙后疼痛、炎症和愈合方面的疗效。在穆尔西亚的一家私人牙科诊所进行了一项单盲随机临床研究,纳入了124名需要拔牙的患者,排除了那些患有可能影响愈合的疾病(如未控制的糖尿病、免疫抑制或出血性疾病)的患者。第一组(实验组):拔牙并使用二极管激光进行PBM治疗(功率:0.5W,能量15J/cm,在距组织1mm处照射10 - 30秒)。第二组(假治疗组):拔牙并应用无效的PBM。随着时间的推移,两组的疼痛和炎症均有相似程度的减轻。两组的焦虑程度均有所下降,但无显著差异(P = 0.776;P = 0.246)。没有证据表明治疗或拔牙部位对愈合有影响。缝合牙槽窝增加了良好愈合的可能性(P = 0.048),而手术时间长则降低了这种可能性(P = 0.040)。PBM是一种非侵入性且安全的治疗方法。本研究未显示与假治疗有显著差异。需要采用标准化方法进行更多研究,以更好地评估其疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b702/12110639/d83ff5eec720/clinpract-15-00090-g001.jpg

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