Dubrow R, Wegman D H
J Natl Cancer Inst. 1983 Dec;71(6):1123-42.
The objectives of this paper were 1) to identify occupations with potentially high cancer risk by combining the results of 12 major occupational disease surveillance studies, 2) to develop a quantitative methodology for accomplishing the first objective, and 3) to make recommendations concerning priorities for occupational cancer research and control on the basis of the results of this analysis in conjunction with other available epidemiologic, industrial hygiene, toxicologic, and employment data. It was suggested that the first priority be the investigation and control of occupational exposure to asbestos, particularly in the automobile repair and construction industries. Of the 34 occupational groups found to be at high risk for lung cancer in this analysis, 18 have potential asbestos exposure. The second priority was suggested to be research into the consistent lung-cancer excess found among motor vehicle drivers. This excess may be due to occupational exposure to diesel and gasoline engine exhaust, to cigarette smoking, or to both of these factors.
1)通过整合12项主要职业病监测研究的结果,识别出具有潜在高癌症风险的职业;2)开发一种用于实现第一个目标的定量方法;3)结合该分析结果以及其他可用的流行病学、工业卫生、毒理学和就业数据,就职业癌症研究和控制的优先事项提出建议。有人建议首要优先事项是调查和控制职业性石棉暴露,尤其是在汽车修理和建筑行业。在该分析中发现的34个肺癌高风险职业群体中,有18个存在潜在石棉暴露。第二个优先事项被建议为研究机动车驾驶员中持续存在的肺癌超额现象。这种超额现象可能是由于职业性接触柴油和汽油发动机尾气、吸烟或这两种因素共同导致的。