皮质内侧杏仁核损伤、行为、皮质酮和催乳素：效应的意外分离
Corticomedial amygdala lesions, behavior, corticosterone, and prolactin: unexpected separation of effects.
作者信息
Seggie J
出版信息
Psychiatry Res. 1983 Oct;10(2):139-50. doi: 10.1016/0165-1781(83)90113-0.
The present experiment examines hormone: behavior relationships following lesions of the amygdala. Affective behavior and levels of corticosterone and prolactin were compared in rats with lesions of the corticomedial amygdala and in nonlesioned and sham-operated controls. Animals with lesions of the corticomedial amygdala were found to be hyperreactive, but to have normal corticosterone and prolactin resting levels and responses to stimulation. The unexpected separation of behavior and hormone responses is compared with behavior and endocrine changes seen following other limbic system lesions, and the implications for the psychoneuroendocrinology of stress are discussed.
本实验研究了杏仁核损伤后的激素与行为关系。对皮质内侧杏仁核损伤的大鼠以及未损伤和假手术对照组的情感行为、皮质酮和催乳素水平进行了比较。结果发现，皮质内侧杏仁核损伤的动物反应过度，但皮质酮和催乳素的静息水平及对刺激的反应正常。将行为与激素反应的意外分离与其他边缘系统损伤后的行为和内分泌变化进行了比较，并讨论了其对应激心理神经内分泌学的意义。
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