Seggie J
Psychiatry Res. 1979 Dec;1(3):283-95. doi: 10.1016/0165-1781(79)90010-6.
The present experiment examines hormone-behavior relationships following manipulation of the amygdala. Affective behavior and levels of corticosterone and prolactin were compared in rats with lesions of the basolateral amygdala and in nonlesioned and sham-operated controls. Animals with lesions of the basolateral amygdala were found to be hyperreactive and to have normal resting levels of corticosterone and prolactin but potentiated corticosterone responses to stress. Normal prolactin stress responses were unaltered by the lesion. The results are discussed in relation to behavioral and endocrine changes seen following other limbic system lesions.
本实验研究了杏仁核被操控后激素与行为之间的关系。对基底外侧杏仁核受损的大鼠、未受损及假手术对照组大鼠的情感行为、皮质酮和催乳素水平进行了比较。发现基底外侧杏仁核受损的动物反应过度，其皮质酮和催乳素的静息水平正常，但对应激的皮质酮反应增强。催乳素对应激的正常反应不受损伤影响。结合其他边缘系统损伤后出现的行为和内分泌变化对结果进行了讨论。
