Muir J L, Pfister H P
Physiol Behav. 1986;37(2):285-8. doi: 10.1016/0031-9384(86)90234-9.
Prolactin along with corticosterone is a stress responsive hormone. The present study examined the effect of predictable and unpredictable psychological stress on corticosterone and prolactin secretion. Repeated unpredictable exposure to the novelty cage produced a more substantial increase in the level of corticosterone than predictable exposure to the same novelty apparatus. In contrast, predictable novelty stress induced a more substantial elevation in prolactin levels than unpredictable stress. Furthermore, it was observed that both corticosterone and prolactin returned to control levels 30 minutes after the fifth exposure to the novelty cage. It was concluded that the pattern of exposure to novelty is an important paradigm which effects the magnitude of hormonal responding. An important relationship between corticosterone release and prolactin secretion is also indicated.
催乳素与皮质酮一样，是一种应激反应激素。本研究考察了可预测和不可预测的心理应激对皮质酮和催乳素分泌的影响。反复不可预测地暴露于新奇笼子比可预测地暴露于相同新奇装置导致皮质酮水平有更显著的升高。相反，可预测的新奇应激比不可预测的应激诱导催乳素水平有更显著的升高。此外，观察到在第五次暴露于新奇笼子30分钟后，皮质酮和催乳素均恢复到对照水平。得出的结论是，新奇暴露模式是影响激素反应幅度的一个重要范式。这也表明了皮质酮释放与催乳素分泌之间的重要关系。
