Makhyoun N A, Veenema R J, Wechsler M
Urology. 1977 Feb;9(2):140-3. doi: 10.1016/0090-4295(77)90183-2.
A study of 66 patients in whom microscopic foci of prostatic cancer was found in prostatectomies done for benign prostatic hyperplasia revealed in 32 of the 66 cases (48%) that there were in retrospect abnormal rectal findings that should have suggested the possibility of neoplasia. Other abnormalities were elevated serum acid phosphatase (5 patients), asymmetrical enlargement of one lateral prostatic lobe at cystoscopy (7 patients), and unilateral hydroureteronephrosis (7 patients). Urinary retention was the presenting symptoms in 56% of the patients. Difficult enucleation was noted in 41% of the open prostatectomies. The importance of performing careful prostatic biopsy in any suspicious prostatic enlargement is again stressed.
一项针对66例因良性前列腺增生而接受前列腺切除术的患者的研究发现，在这66例患者中的32例（48%）中，回顾性分析发现直肠检查结果异常，这本应提示存在肿瘤的可能性。其他异常情况包括血清酸性磷酸酶升高（5例患者）、膀胱镜检查时一侧前列腺叶不对称增大（7例患者）以及单侧输尿管肾盂积水（7例患者）。56%的患者以尿潴留为首发症状。在41%的开放性前列腺切除术中发现剜除困难。再次强调了对任何可疑前列腺肿大进行仔细前列腺活检的重要性。
