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Cytostatic activity of organic compounds and their average quasi-valence number.

作者信息

Veljković V, Ajdacić V

出版信息

Experientia. 1978 May 15;34(5):639-41. doi: 10.1007/BF01937008.

DOI:10.1007/BF01937008
PMID:658256
Abstract

It is found that the average quasi-valence numbers of alkylating cytostatics lie in the region of potential carcinogens, while the average quasi-valence numbers of antimetabolites predominantly cover the region of noncarcinogens. Implications of this finding on the design of new drugs are discussed.

摘要

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引用本文的文献

1
Antibiotic activity of organic compounds and their average quasi-valence number.
Experientia. 1978 May 15;34(5):633-5. doi: 10.1007/BF01937005.
2
Simple theoretical criterion of chemical carcinogenicity - a refutation.化学致癌性的简单理论标准——一种反驳
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本文引用的文献

1
Theoretical prediction of mutagenicity and carcinogenicity of chemical substances.化学物质致突变性和致癌性的理论预测
Cancer Biochem Biophys. 1976;1(6):295-8.
2
Simple theoretical criterion of chemical carcinogenicity.
Experientia. 1977 Sep 15;33(9):1228-9. doi: 10.1007/BF01922345.