Cytostatic activity of organic compounds and their average quasi-valence number.
作者信息
Veljković V, Ajdacić V
出版信息
Experientia. 1978 May 15;34(5):639-41. doi: 10.1007/BF01937008.
PMID:658256
Abstract
It is found that the average quasi-valence numbers of alkylating cytostatics lie in the region of potential carcinogens, while the average quasi-valence numbers of antimetabolites predominantly cover the region of noncarcinogens. Implications of this finding on the design of new drugs are discussed.
摘要
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