一种新型抗镰变剂：其对S/S红细胞及血红蛋白S作用的体外研究
A new antisickling agent: in vitro studies of its effect on S/S erythrocytes and on hemoglobin S.
作者信息
Adhikary P K, Haynes J K, Patthey H L, Rhodes R S
出版信息
Experientia. 1978 Jun 15;34(6):804-6. doi: 10.1007/BF01947338.
PMID:658310
Abstract
2-(benzoylamino) pyridinium benzoate (BAPB) has exhibited an antisickling effect with homozygous S/S erythrocytes in vitro. This study suggests that BAPB prevents sickling by inhibiting the gelation of hemoglobin S.
摘要
2-（苯甲酰氨基）苯甲酸吡啶鎓（BAPB）在体外对纯合S/S红细胞表现出抗镰变作用。本研究表明，BAPB通过抑制血红蛋白S的凝胶化来防止镰变。
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