Plasma prostaglandin activities in some immuno-inflammatory diseases.

In the present study the relationship between plasma prostaglandins (PGs) level and the immuno-inflammatory reactions, known to accompany bronchial asthma and/or schistosomiasis infection, was investigated. It was found that plasma PGF2 alpha increased significantly above the control values in 30 asthmatics, 30 schistosomal and 30 asthmatic schistosomal patients. Plasma PGE increased also together with that of PGF2 alpha which is considered to be useful for the protection of the patient against the injurious effects of the infection, due to the known opposing actions of PGE to those of PGF2 alpha.