Zakharian A K, Amatuni V G
Vopr Med Khim. 1991 May-Jun;37(3):45-7.
Dynamics of alterations in content of prostaglandins (PG) F2 alpha and E and in the ratio PGF2 alpha/PGE was studied in blood plasma of 24 patients with chronic asthmatic bronchitis and 109 patients with bronchial asthma. Alterations in content of PGF2 alpha correlated with severity of the disease, while PGE content was similarly below the control values in all the groups examined. The ratio PGF2 alpha/PGE corresponded with the alterations in content of PGF2 alpha. Direct correlation was observed between content of adrenaline, PGF2 alpha and the rate of lipid peroxidation, whereas PGE was not related to these patterns. The correlation was completely absent under conditions of asthmatic attack.
研究了24例慢性喘息性支气管炎患者和109例支气管哮喘患者血浆中前列腺素（PG）F2α和E的含量变化以及PGF2α/PGE比值的变化。PGF2α含量的变化与疾病严重程度相关，而在所有检查组中PGE含量同样低于对照值。PGF2α/PGE比值与PGF2α含量的变化相对应。观察到肾上腺素、PGF2α含量与脂质过氧化速率之间存在直接相关性，而PGE与这些模式无关。在哮喘发作时这种相关性完全不存在。
