Cerezo L, Head D R, Pullen J, Humphrey B
Am J Clin Pathol. 1984 Mar;81(3):355-7. doi: 10.1093/ajcp/81.3.355.
To evaluate the prevalence and significance of hand-mirror cells (HMC) in acute leukemia, 214 cases were studied retrospectively. They were classified by FAB and included 102 pediatric and 112 adult cases. Greater than 10% HMC were found in 6.5%. No overall difference was noted with age group, though HMC were more common in lymphoblastic cases (10% versus 3%). However, the greatest number of HMC were found in four adult cases, three of which were myeloblastic. Of the lymphoblastic cases with greater than 10% HMC, T and B studies were done in three that were typed as one T cell and two non-T cell (L1, CALL+; L3, sIg+). Forty-eight other cases with less than 10% HMC included 13 T cell and 35 non-T cell. The authors conclude that HMC may not correlate with morphologic or immune cell type and they do not appear to be a specific marker for a type of lymphoblastic and/or T-cell leukemia.
为评估手镜细胞（HMC）在急性白血病中的发生率及意义，对214例病例进行了回顾性研究。这些病例按FAB分类，包括102例儿童病例和112例成人病例。6.5%的病例中发现HMC超过10%。各年龄组之间未发现总体差异，不过HMC在淋巴细胞白血病病例中更为常见（10%对3%）。然而，HMC数量最多的是4例成人病例，其中3例为粒细胞白血病。在HMC超过10%的淋巴细胞白血病病例中，对3例进行了T和B研究，其中1例为T细胞型，2例为非T细胞型（L1，CALL+；L3，sIg+）。其他48例HMC低于10%的病例包括13例T细胞型和35例非T细胞型。作者得出结论，HMC可能与形态学或免疫细胞类型无关，它们似乎不是淋巴细胞白血病和/或T细胞白血病某一类型的特异性标志物。
