Gelhard T B, Arends J
J Biol Buccale. 1984 Mar;12(1):59-65.
The purpose of this work was to investigate mineral deposition and redistribution in subsurface human artificial enamel lesions during in vivo remineralization period of 3 months. The enamel lesions were placed in lower prostheses of 30 patients, divided in 3 groups. Group A brushed daily with H2O; group B brushed with H2O and rinsed with a neutral 50 ppm F solution and group C brushed with a neutral 1500 ppm F toothpaste. The technique employed was microradiography. Initially the average vol % of mineral in the lesion body was 47%. After 3 months remineralization in vivo the vol % of mineral in the lesion body was for group A, B and C: 50.7, 48.7 and 53.1 vol %, respectively. The average lesion depth decreased for groups A, B and C 18, 13 and 25 microns respectively over 3 months. The original lesion depth was +/- 100 microns. The microradiographic data show conclusively that mineral is deposited "de novo" inside subsurface lesions. The remineralization percentages are for the control, rinse and brush group 20%, 15% and 31%, respectively.
本研究的目的是调查在3个月的体内再矿化期间,人类人工牙釉质表层下病变中矿物质的沉积和重新分布情况。将牙釉质病变置于30名患者的下颌假牙中,分为3组。A组每天用清水刷牙;B组用清水刷牙并用50 ppm的中性氟溶液漱口;C组用1500 ppm的中性含氟牙膏刷牙。采用的技术是显微放射照相术。最初,病变体中矿物质的平均体积百分比为47%。在3个月的体内再矿化后,A组、B组和C组病变体中矿物质的体积百分比分别为50.7%、48.7%和53.1%。在3个月的时间里,A组、B组和C组的平均病变深度分别减少了18微米、13微米和25微米。原始病变深度为±100微米。显微放射照相数据确凿地表明,矿物质在表层下病变内部“重新形成”。对照组、漱口组和刷牙组的再矿化百分比分别为20%、15%和31%。