Mehta A B, Goldman J M, Kohner E
Br J Haematol. 1984 Apr;56(4):661-7. doi: 10.1111/j.1365-2141.1984.tb02190.x.
We describe three patients with chronic granulocytic leukaemia who developed impaired visual acuity in association with high leucocyte counts. Two of the patients were in the chronic phase of their disease and the third developed visual symptoms at the time of blastic transformation. Fundoscopy showed retinal haemorrhages and exudates and a vascular picture consistent with hyperviscosity. We propose the term 'hyperleucocytic retinopathy' for these appearances. Two of the patients derived rapid benefit following leucapheresis and the visual acuity of the third patient improved following treatment with cytotoxic drugs.
我们描述了3例慢性粒细胞白血病患者，他们在白细胞计数高的情况下出现了视力受损。其中2例患者处于疾病的慢性期，第3例在急变期出现了视觉症状。眼底镜检查显示视网膜出血和渗出，以及与血液高黏滞度相符的血管表现。我们建议将这些表现称为“高白细胞性视网膜病变”。其中2例患者在进行白细胞单采术后迅速获益，第3例患者在接受细胞毒性药物治疗后视力有所改善。
