Andersson K E, Nyberg L
Eur J Respir Dis Suppl. 1984;134:165-70.
Terbutaline is widely used in respiratory medicine, in obstetrics and to some extent in cardiovascular medicine. The growing use of the drug has increased the need of pharmacokinetic information to design and optimize therapy. The clinical pharmacokinetics of terbutaline are briefly reviewed and discussed with special consideration given to therapeutic plasma concentration, bioavailability, volume of distribution, clearance and half-life of elimination.
特布他林广泛应用于呼吸医学、产科,并在一定程度上应用于心血管医学。该药物使用的增加,使得设计和优化治疗方案时对药代动力学信息的需求也相应增加。本文简要回顾并讨论了特布他林的临床药代动力学,特别关注了治疗性血浆浓度、生物利用度、分布容积、清除率和消除半衰期。