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一种短寿命爬行类动物骨骼肌中胶原蛋白和非胶原蛋白的年龄相关变化。

Age-related changes in collagenous and noncollagenous proteins of skeletal muscle of a short-lived species of reptile.

作者信息

Haseeb M A, Patnaik B K

出版信息

Gerontology. 1978;24(5):343-7. doi: 10.1159/000212269.

DOI:10.1159/000212269
PMID:658671
Abstract

The collagenous/noncollagenous protein ratio in the skeletal muscle of the male garden lizard increased with advancing age, suggesting increased tensile strength of aged muscle. The solubility of collagen and the soluble/insoluble collagen ratio showed a decline during ageing confirming the development of cross-linkages in the muscle collagen of ageing lizards. It is suggested that these changes are likely to disturb the efficiency of ageing muscle.

摘要

雄性园蜥骨骼肌中胶原蛋白/非胶原蛋白的比例随着年龄的增长而增加,这表明老年肌肉的拉伸强度增加。胶原蛋白的溶解度以及可溶性/不溶性胶原蛋白的比例在衰老过程中呈现下降趋势,这证实了衰老蜥蜴肌肉胶原蛋白中交联的形成。有人认为,这些变化可能会干扰老年肌肉的效率。

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