Hood I C, Qizilbash A H, Salama S S, Young J E, Archibald S D
Acta Cytol. 1984 May-Jun;28(3):305-12.
Sebaceous carcinoma is uncommon and usually presents in the ocular adnexae as cancer of the meibomian glands. That cutaneous sebaceous carcinoma generally occurs along with other epidermal elements has caused some nosologic confusion; tumors in which sebaceous elements predominate are encountered rarely. They are aggressive tumors in any location but particularly around the ocular adnexae, necessitating wide excision and careful follow-up to detect metastases. At our institution two such tumors were excised recently, one from the eyelid and one from previously irradiated skin. Subsequent metastases were detected without difficulty on needle aspiration cytology, which produced characteristic epithelial cells with bubbly , lipid-rich cytoplasm. The cytologic, histologic and ultrastructural appearances of these tumors that are suited to diagnosis on fine needle aspirates are reported.
皮脂腺癌并不常见，通常表现为睑板腺癌，发生于眼附属器。皮肤皮脂腺癌一般与其他表皮成分同时出现，这导致了一些疾病分类学上的混淆；以皮脂腺成分占主导的肿瘤很少见。皮脂腺癌在任何部位都是侵袭性肿瘤，尤其是在眼附属器周围，因此需要广泛切除并仔细随访以检测转移情况。在我们机构，最近切除了两例这样的肿瘤，一例来自眼睑，另一例来自先前接受过放疗的皮肤。随后在针吸细胞学检查中不难检测到转移，针吸细胞学检查产生了具有泡沫状、富含脂质细胞质的特征性上皮细胞。本文报告了这些肿瘤的细胞学、组织学和超微结构表现，这些表现适合于细针穿刺抽吸诊断。
