Brandt S K, Bugg J L
Dent Clin North Am. 1984 Jul;28(3):563-79.
During the course of dental treatment, when it is necessary to prescribe pharmacologic agents for the pediatric patient, a drug should be selected that is not only effective but also available in a readily acceptable form. Dosages should be considered carefully. Rather than attempting to adjust adult recommendations, established guidelines for children should be utilized. Manufacturer's doses should be followed when available. If a child frustrates efforts toward treatment and does not respond to nonpharmacotherapeutic management approaches, premedication should be considered. The practitioner should have a thorough medical history before deciding to employ outpatient sedation. This history can be helpful in selecting the most appropriate regimen. Very young children and severely compromised patients are not good candidates for sedation and are best treated under general anesthesia. Narcotic analgesics are rarely indicated for control of pain following dental treatment in children. Nonnarcotic preparations are very effective and will suffice for most procedures. Because prolonged bleeding has been demonstrated, aspirin should be used with caution in surgical cases. Oral administration is recommended for most dental infections requiring antibiotics. In instances when severe infection is encountered, the parenteral route is suggested. A narrow-spectrum, bactericidal agent is preferred; barring allergy, penicillin is the usual drug of choice. When antibiotic prophylaxis is indicated, adherence to American Heart Association guidelines is strongly encouraged.
在牙科治疗过程中,当有必要为儿科患者开药物时,应选择一种不仅有效而且有易于接受剂型的药物。应仔细考虑剂量。不应试图调整成人用药建议,而应采用既定的儿童用药指南。有可用的制造商剂量时应遵循。如果儿童在治疗过程中不配合且对非药物治疗方法无反应,则应考虑预先用药。从业者在决定采用门诊镇静之前应了解完整的病史。该病史有助于选择最合适的治疗方案。非常年幼的儿童和严重受损的患者不是镇静的合适人选,最好在全身麻醉下进行治疗。儿童牙科治疗后很少需要使用麻醉性镇痛药来控制疼痛。非麻醉性制剂非常有效,对大多数操作来说足够了。由于已证明阿司匹林会导致出血时间延长,在手术病例中应谨慎使用。大多数需要使用抗生素的牙科感染建议口服给药。遇到严重感染的情况时,建议采用肠胃外给药途径。首选窄谱杀菌剂;除非有过敏反应,通常首选青霉素。当需要进行抗生素预防时,强烈鼓励遵循美国心脏协会的指南。