Hastings A
Proc Natl Acad Sci U S A. 1984 Jul;81(14):4596-8. doi: 10.1073/pnas.81.14.4596.
The minimum strength of selection necessary to maintain high linkage disequilibrium in two-locus, two-allele, deterministic discrete time genetic models with high rates of partial selfing is determined. The relationship between linkage and partial selfing is shown to be complex. The major effect of high selfing rates is to decrease the strength of selection necessary to maintain disequilibrium, but only for large recombination rates. With partial selfing, stable equilibria of these models require strong selection to maintain high values of disequilibrium.
确定了在具有高比率部分自交的两基因座、两等位基因、确定性离散时间遗传模型中维持高连锁不平衡所需的最小选择强度。连锁与部分自交之间的关系被证明是复杂的。高自交率的主要影响是降低维持不平衡所需的选择强度，但仅适用于大重组率。对于部分自交，这些模型的稳定平衡需要强选择来维持高不平衡值。
