Barabas G, Matthews W S, Ferrari M
Arch Neurol. 1984 Aug;41(8):871-2. doi: 10.1001/archneur.1984.04050190077018.
Among 60 patients with Tourette's syndrome (TS), whose mean age was 11.9 years, migraine was prevalent in 26.6%. This figure is substantially greater than that reported for the general population of school-aged children (4.0% to 7.4%) or for two control groups consisting of children with seizure disorders (n = 72) and learning disabilities (n = 62). The prevalence rates for these two control groups were 11.3% and 8.0%, respectively. The hypothesis is offered that the coexistence of TS and migraine in a subgroup of children with TS may reflect a similar abnormality underlying both conditions; specifically, neurohumoral dysfunction involving serotonin metabolism.
在60例平均年龄为11.9岁的图雷特综合征（TS）患者中，偏头痛的患病率为26.6%。这一数字显著高于学龄儿童总体人群（4.0%至7.4%）或由癫痫症患儿（n = 72）和学习障碍患儿（n = 62）组成的两个对照组所报告的数字。这两个对照组的患病率分别为11.3%和8.0%。有人提出这样的假说，即TS患儿亚组中TS与偏头痛的共存可能反映了两种疾病潜在的相似异常；具体而言，是涉及血清素代谢的神经体液功能障碍。
