Orr D P, Myerowitz R L, Herbert D L, Friday P
Invest Radiol. 1978 Mar-Apr;13(2):110-4. doi: 10.1097/00004424-197803000-00002.
Intimal calcific atherosclerosis may lead to diminished organ perfusion, whereas medial calcification (Mönckeberg type) is of no physiologic significance. Thirty-nine excised arteries were studied by correlating specimen radiographs with transverse histologic sections to determine whether intimal and medial calcification could be reliably distinguished by radiographic criteria. The calcification was correctly localized in 92% of the arteries studied. Intimal calcification was usually irregular and patchy, whereas medial calcification was regular and diffuse. In one case, extensive medial calcification obscured intimal disease. Plain radiographs may be a useful way to follow progression, regression and the effects of therapy on vaso-occlusive disease in certain high-risk patients.
内膜钙化性动脉粥样硬化可能导致器官灌注减少，而中膜钙化（门克贝格型）无生理意义。通过将标本X线片与横向组织学切片相关联，对39条切除的动脉进行研究，以确定能否通过X线标准可靠地区分内、中膜钙化。在92%的研究动脉中钙化定位正确。内膜钙化通常不规则且呈斑片状，而中膜钙化则规则且弥漫。有1例中，广泛的中膜钙化掩盖了内膜病变。对于某些高危患者，普通X线片可能是一种有用的方法，用于跟踪血管闭塞性疾病的进展、消退及治疗效果。
