Bles W, de Jong J M, Rasmussens J J
Acta Otolaryngol Suppl. 1984;406:101-4. doi: 10.3109/00016488309123013.
Bilabyrinthless subjects, i.e. subjects clinically devoid of labyrinthine responses, show a greater than normal decrease in postural stability following eye closure. Because changes in head position, which affect posture in healthy subjects, do not do so in bilabyrinthless patients, static afferent information from healthy neck receptors does not contribute to postural stabilization. Somatosensory nystagmus and dynamic cervico-ocular responses are equally greater in bilabyrinthless than normal subjects, which indicates that both categories of eye movements are mediated by the same mechanism. Optokinetic nystagmus is slightly diminished in bilabyrinthless patients and optokinetic after-nystagmus was mostly absent. In terms of the Raphan-Cohen model our findings confirm that destruction of the labyrinthine function abolishes the vestibulo-ocular integrator function.
双侧迷路缺失的受试者，即临床上没有迷路反应的受试者，在闭眼后姿势稳定性的下降比正常情况更明显。由于影响健康受试者姿势的头部位置变化在双侧迷路缺失的患者中不会产生同样的影响，来自健康颈部感受器的静态传入信息对姿势稳定没有作用。双侧迷路缺失的受试者的躯体感觉性眼球震颤和动态颈眼反射同样比正常受试者更强烈，这表明这两类眼球运动是由相同机制介导的。双侧迷路缺失的患者视动性眼球震颤略有减弱，且大多没有视动后眼震。根据拉方-科恩模型，我们的研究结果证实，迷路功能的破坏消除了前庭眼整合功能。
