Gangrade B K, Dominic C J
Exp Clin Endocrinol. 1984 Jul;84(1):13-9. doi: 10.1055/s-0029-1210361.
Unisexual grouping of female mice induced irregularities in their oestrous cycles. However, no significant difference in body weight and in the weights of adrenals, uteri and ovaries and in the adrenal delta 5 3 beta-hydroxysteroid dehydrogenase (HSD) activity was found between unisexually grouped females and individually housed females. Adrenalectomy of females failed to prevent the oestrous cycle irregularities induced by unisexual grouping. Furthermore, adrenalectomized females in unisexual groups responded to exposure to males by exhibiting oestrus acceleration and synchronization (the Whitten effect). The results rule out the involvement of the adrenals in the oestrous cycle irregularities induced by unisexual grouping and in the induction of the Whitten effect in unisexually grouped females.
将雌性小鼠单性分组会导致其发情周期出现异常。然而，单性分组的雌性小鼠与单独饲养的雌性小鼠在体重、肾上腺、子宫和卵巢的重量以及肾上腺δ5 3β-羟基类固醇脱氢酶（HSD）活性方面未发现显著差异。对雌性小鼠进行肾上腺切除并不能预防单性分组所诱导的发情周期异常。此外，单性组中接受肾上腺切除的雌性小鼠在接触雄性时会出现发情加速和同步现象（惠顿效应）。这些结果排除了肾上腺参与单性分组所诱导的发情周期异常以及单性分组雌性小鼠中惠顿效应诱导过程的可能性。
