Corson S L, Batzer F R, Alexander N J, Schlaff S, Otis C
Fertil Steril. 1984 Nov;42(5):756-60.
The Ericsson albumin filtration technique was used to collect a fraction rich in Y sperm for selective insemination in couples desiring a male infant. Of 35 conceptions in which sex was known at delivery or spontaneous abortion, there were 28 males (80%). Twelve pregnancies were achieved after separation of sperm in a Sephadex gel filtration system designed to allow for collection of a fraction enriched in X sperm. Seven pregnancies have resulted in females, two in males, and one in twins of each sex. One patient aborted, and one is still pregnant. While selection for either sex can be done electively, on the basis of sociologic preference, female selection has, as an additional indication, avoidance of male offspring to carriers of sex-linked diseases.
采用爱立信白蛋白过滤技术收集富含Y精子的部分,用于希望生育男婴的夫妇进行选择性授精。在35例分娩或自然流产时已知性别的妊娠中,有28例为男性(80%)。在一个旨在收集富含X精子部分的葡聚糖凝胶过滤系统中分离精子后,有12例妊娠成功。7例妊娠结果为女性,2例为男性,1例为各有一男一女的双胞胎。1例患者流产,1例仍在妊娠中。虽然可以根据社会偏好选择性地进行任何一种性别的选择,但女性选择除了社会偏好外,还有一个额外的指征,即对于性连锁疾病携带者而言,可避免生育男性后代。