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通过精子白蛋白分离进行性别预选。

Sex preselection through albumin separation of sperm.

作者信息

Beernink F J, Dmowski W P, Ericsson R J

机构信息

East Bay Fertility Obstetrics-Gynecology Medical Group, Berkeley, California 94705.

出版信息

Fertil Steril. 1993 Feb;59(2):382-6.

PMID:8425635
Abstract

OBJECTIVE

To determine if passage of sperm through columns of liquid albumin before their use in artificial insemination could affect the sex ratio at birth.

DESIGN

Sperm were isolated by layering over columns of liquid albumin. The isolated fractions were inseminated into the uterus on the presumptive day of ovulation.

SETTING

Patients were treated in 65 clinical practices (Sperm Centers) located both in this country (57) and abroad (8).

PATIENTS

Individuals were self-selected by their desire to have a child of a specified sex.

MAIN OUTCOME MEASURE

The sex of offspring resulting from the insemination of isolated sperm.

RESULTS

Insemination with sperm isolated to enhance male sex preselection produced 71% and 76% males depending on the technique. Use of isolated sperm in women who were taking clomiphene citrate was associated with a 69% birth of females.

CONCLUSIONS

Separation of sperm on columns of liquid albumin can affect the sex ratio at birth.

摘要

目的

确定在人工授精前让精子通过液体白蛋白柱是否会影响出生时的性别比例。

设计

通过在液体白蛋白柱上分层分离精子。在推测的排卵日将分离出的部分精子注入子宫。

地点

患者在本国(57个)和国外(8个)的65个临床机构(精子中心)接受治疗。

患者

个体根据其想要特定性别的孩子的愿望自行选择。

主要观察指标

分离出的精子授精后所生后代的性别。

结果

根据技术不同,分离用于增强男性性别预选的精子进行授精后,男性出生比例分别为71%和76%。在服用枸橼酸氯米芬的女性中使用分离出的精子,女性出生比例为69%。

结论

在液体白蛋白柱上分离精子会影响出生时的性别比例。

相似文献

1
Sex preselection through albumin separation of sperm.通过精子白蛋白分离进行性别预选。
Fertil Steril. 1993 Feb;59(2):382-6.
2
Experiences in Hong Kong with the theory and practice of the albumin column method of sperm separation for sex selection.香港在用于性别选择的精子分离白蛋白柱法理论与实践方面的经验。
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3
The clinical relevance of sex selection techniques.性别选择技术的临床相关性。
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Female sex selection using clomiphene citrate and albumin separation of human sperm.使用枸橼酸氯米芬和人精子白蛋白分离法进行女性性别选择。
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Male sex preselection through sperm isolation.通过精子分离进行男性性别预选。
Fertil Steril. 1982 Oct;38(4):493-5.
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Sex selection by sperm separation and insemination.通过精子分离和授精进行性别选择。
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Infertility: a health problem in the Muslim world.不孕不育:穆斯林世界的一个健康问题。
Popul Sci. 1991 Jan;10:41-58.
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Sex preselection in rabbits: live births from X and Y sperm separated by DNA and cell sorting.家兔的性别预选:通过DNA和细胞分选分离X和Y精子后的活产仔。
Biol Reprod. 1989 Aug;41(2):199-203. doi: 10.1095/biolreprod41.2.199.
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