家族性良性高钙血症（FBH；McK.编号14598，1983）：对一个荷兰大家庭的连锁研究
Familial benign hypercalcaemia (FBH; McK. No. 14598, 1983): linkage studies in a large Dutch family.
作者信息
Menko F H, Bijvoet O L, Meera Khan P, Nijenhuis L E, von Loghem E, Schreuder I, Bernini L F, Pronk J C, Madan K, Went L N
出版信息
Hum Genet. 1984;67(4):452-4. doi: 10.1007/BF00291409.
By screening 27 hypercalcaemic and 21 normocalcaemic subjects in a large Dutch pedigree with familial benign hypercalcaemia (FBH; McK. No. 14598) (McKusick 1983) for more than 35 genetic markers, it was found that linkage of FBH can be excluded at about 25 centimorgans (cM) from GM, 20 cM from ABO, 15 cM from MNS and HLA, 10 cM from JK and PI, and 5 cM each from ACP1, AK1, ADA, GPT1, and PGP.
通过对一个患有家族性良性高钙血症（FBH；McK.编号14598）（麦库西克，1983年）的荷兰大家族中的27名高钙血症患者和21名血钙正常的受试者进行筛查，检测超过35个遗传标记，结果发现，FBH与GM的连锁距离约为25厘摩（cM）、与ABO为20 cM、与MNS和HLA为15 cM、与JK和PI为10 cM、与ACP1、AK1、ADA、GPT1和PGP均为5 cM，从而可以排除FBH与这些标记的连锁关系。
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