人类6号染色体上的C波段多态性。

C-band polymorphism in human chromosome no. 6.

作者信息

Madan K, Bruinsma A H

出版信息

Clin Genet. 1979 Feb;15(2):193-7. doi: 10.1111/j.1399-0004.1979.tb01761.x.

DOI:10.1111/j.1399-0004.1979.tb01761.x

Abstract

Chromosome analysis of G-banded cells from 92 individuals consecutively referred to the Cytogenetics Laboratory show that the paracentromeric band in the short arm (6p11), which stains negatively with G-banding and darkly with C-banding, shows a marked increase in size in about 9% of chromosome no. 6. The results of this study and those from a family in which two variants of chromosome no. 6 are segregating are compatible with a Mendelian pattern of inheritance.

摘要

对连续送往细胞遗传学实验室的92名个体的G带细胞进行染色体分析，结果显示，6号染色体短臂（6p11）上的着丝粒旁带在G带染色时呈阴性，在C带染色时呈深色，约9%的6号染色体上该带的大小显著增加。本研究结果以及一个6号染色体两种变体正在分离的家系的研究结果与孟德尔遗传模式相符。