Buckley J A, Ciancio S G, McMullen J A
J Periodontol. 1984 Nov;55(11):653-7. doi: 10.1902/jop.1984.55.11.653.
Blood loss in periodontal flap surgery using lidocaine 2% with either 1:50,000 or 1:100,000 epinephrine was compared. Ten patients from the graduate periodontal clinic were selected for the study. After the initial therapy which included oral hygiene instruction, scaling and root planning and occlusal adjustment, 20 surgical procedures were performed. In any one patient if 1:50,000 epinephrine was used on the posterior sextant of an arch, then 1:100,000 epinephrine was used on the contralateral side, with similar volumes being injected by the same method. Blood loss was determined by the cyanmethemoglobin comparison technique. Procedures using lidocaine 2% with 1:100,000 epinephrine generally had more than twice as much blood loss as those using lidocaine 2% with 1:50,000 epinephrine.
比较了在牙周瓣手术中使用含1:50,000或1:100,000肾上腺素的2%利多卡因时的失血量。从牙周科研究生门诊选取了10名患者进行该研究。在包括口腔卫生指导、洁治和根面平整以及咬合调整的初始治疗后，进行了20次手术操作。在任何一名患者中，如果在牙弓的后牙区段使用1:50,000肾上腺素，那么在对侧使用1:100,000肾上腺素，且通过相同方法注射相同体积的药物。失血量通过氰化高铁血红蛋白比较技术测定。使用含1:100,000肾上腺素的2%利多卡因的手术操作的失血量通常是使用含1:50,000肾上腺素的2%利多卡因的手术操作的两倍以上。
