血小板活化因子刺激肽白三烯释放：血管活性多肽的抑制作用。
Platelet-activating factor stimulation of peptidoleukotriene release: inhibition by vasoactive polypeptide.
作者信息
Beaubien B B, Tippins J R, Morris H R
出版信息
Biochem Biophys Res Commun. 1984 Nov 30;125(1):105-8. doi: 10.1016/s0006-291x(84)80340-x.
PMID:6594998
Abstract
Leukotriene (LT) release stimulated by platelet activating factor was inhibited by vasoactive intestinal polypeptide (VIP) in an in vitro rat lung preparation. This was detected by HPLC and radioimmunoassay. LTC4, although the major species in the stimulatory model used, was not detected in peptide-treated preparations and LTD4 and LTE4 levels were considerably reduced.
摘要
在体外大鼠肺制备实验中，血管活性肠肽（VIP）抑制了血小板活化因子刺激的白三烯（LT）释放。这是通过高效液相色谱法（HPLC）和放射免疫测定法检测到的。虽然LTC4是所用刺激模型中的主要成分，但在肽处理的制剂中未检测到，并且LTD4和LTE4水平显著降低。
Zotero 插件