急性髓系白血病中的血小板缺陷。
The platelet defect in acute myeloid leukaemia.
作者信息
Woodcock B E, Cooper P C, Brown P R, Pickering C, Winfield D A, Preston F E
出版信息
J Clin Pathol. 1984 Dec;37(12):1339-42. doi: 10.1136/jcp.37.12.1339.
Abstract
In a study of platelets from 13 patients with acute myeloid leukaemia abnormal aggregation and release reactions were found. A previously unrecognised quantitative defect of thromboxane B2 production may, at least in part, explain these findings. In contrast to a previous report, we were unable to show a convincing storage pool defect in these platelets. The platelet membrane glycoproteins were largely normal.
摘要
在一项对13例急性髓细胞白血病患者血小板的研究中，发现了异常的聚集和释放反应。一种先前未被认识的血栓素B2生成的定量缺陷可能至少部分地解释了这些发现。与之前的一份报告相反，我们未能在这些血小板中显示出令人信服的储存池缺陷。血小板膜糖蛋白在很大程度上是正常的。
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