Van Cauwenberge P B
Acta Otolaryngol Suppl. 1984;414:147-53. doi: 10.3109/00016488409122897.
A prospective epidemiologic study in 2065 healthy children aged 21/2 to 6 years to determine the incidence of secretory otitis media (SOM) also provided information about the role of various factors that are suggested to predispose to SOM. The results of this study were compared with earlier reports by other authors. The factors could be classified into four groups: predisposing factors without any doubt, factors without any significant influence on SOM, controversial factors, and factors that are not sufficiently documented. Particular attention is paid to upper respiratory tract infections, systemic disorders, age, race, sex, maturity at birth, environmental factors, consumption of antibiotics and genetic predisposition.
一项针对2065名2岁半至6岁健康儿童的前瞻性流行病学研究，旨在确定分泌性中耳炎（SOM）的发病率，同时也提供了有关各种被认为易患SOM的因素的作用的信息。本研究结果与其他作者早期的报告进行了比较。这些因素可分为四类：毫无疑问的易感因素、对SOM无任何显著影响的因素、有争议的因素以及记录不充分的因素。特别关注上呼吸道感染、全身性疾病、年龄、种族、性别、出生时的成熟度、环境因素、抗生素使用和遗传易感性。
