Keller F S, Rösch J, Dotter C T
Radiology. 1983 Mar;146(3):615-9. doi: 10.1148/radiology.146.3.6600845.
Absolute ethanol was evaluated as a vaso-obliterative agent in 15 patients with bleeding of gastroesophageal varices. Initial control of hemorrhaging was obtained in 13 (87%). Two patients died from unrelated causes within 48 hours of the procedure. Variceal bleeding recurred in seven of the 11 remaining patients (64%) from one week to 13 months after embolization. Four patients did not rebleed; two of them died (4 weeks and 6 months after the procedure), and two are alive (14 and 16 months after the procedure). Significant disadvantages of ethanol for obliteration of gastroesophageal varices (marked prolongation of procedure time and lack of radio-opacity) probably contributed to the high incidence of portal vein thrombosis (3 patients [20%]).
对15例胃食管静脉曲张出血患者评估了无水乙醇作为血管闭塞剂的效果。13例(87%)患者出血得到初步控制。2例患者在该操作后48小时内死于无关原因。其余11例患者中有7例(64%)在栓塞后1周 至13个月出现静脉曲张出血复发。4例患者未再出血;其中2例死亡(操作后4周和6个月),2例存活(操作后14个月和16个月)。乙醇用于闭塞胃食管静脉曲张的显著缺点(操作时间明显延长和缺乏放射不透性)可能导致门静脉血栓形成的发生率较高(3例患者[20%])。