毛细胞的性质——一组单克隆抗体的研究
The nature of hairy cells - a study with a panel of monoclonal antibodies.
作者信息
Worman C P, Brooks D A, Hogg N, Zola H, Beverley P C, Cawley J C
出版信息
Scand J Haematol. 1983 Mar;30(3):223-6. doi: 10.1111/j.1600-0609.1983.tb01479.x.
In all 11 patients with hairy-cell leukaemia (HCL) tested, a high percentage of peripheral blood and splenic (3 cases) hairy cells (HCs) reacted with 2 B-cell-specific monoclonal antibodies (FMC1 and FMC7), but failed to stain with 5 monocyte/macrophage-specific (FMC17, UCHM1, SM1, SMø and OKM1) and with 4 T-cell-specific antibodies (UCHT1, Leu1, 2a and 3a). The data provide further evidence in support of the B-cell nature of the HCs of HCL.
在接受检测的所有11例毛细胞白血病（HCL）患者中，外周血及脾脏（3例）中的高比例毛细胞（HC）与2种B细胞特异性单克隆抗体（FMC1和FMC7）发生反应，但与5种单核细胞/巨噬细胞特异性抗体（FMC17、UCHM1、SM1、SMø和OKM1）以及4种T细胞特异性抗体（UCHT1、Leu1、2a和3a）均未发生染色反应。这些数据为支持HCL中HC的B细胞性质提供了进一步的证据。
Zotero 插件