中等剂量醋酸甲泼尼龙肌肉注射治疗风湿性疾病
Intermediate-dose intramuscular methylprednisolone acetate in the treatment of rheumatic disease.
作者信息
Kovarsky J
出版信息
Ann Rheum Dis. 1983 Jun;42(3):308-10. doi: 10.1136/ard.42.3.308.
Abstract
Treatment with a high-dose, intravenous bolus of methylprednisolone has been reported in numerous cases of rheumatic diseases. The optimal routes of administration, dosage, dosage interval, and other factors are unknown. This report describes uncontrolled clinical observations with a single dose of 320 mg of intramuscular methylprednisolone acetate in patients with rheumatic disease (12 with rheumatoid arthritis, 2 with spondyloarthropathy). This treatment may provide a useful therapeutic adjunct in selected clinical circumstances.
摘要
在众多风湿性疾病病例中，已有使用大剂量静脉推注甲基泼尼松龙的报道。最佳给药途径、剂量、给药间隔及其他因素尚不清楚。本报告描述了对患有风湿性疾病的患者（12例类风湿关节炎、2例脊柱关节病）单次肌内注射320mg醋酸甲基泼尼松龙的非对照临床观察。这种治疗方法在特定临床情况下可能是一种有用的治疗辅助手段。
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本文引用的文献
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Ann Intern Med. 1981 Jan;94(1):21-6. doi: 10.7326/0003-4819-94-1-21.
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Sudden death after methylprednisolone pulse therapy.甲泼尼龙冲击疗法后猝死。
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