W/Wv基因型遗传性贫血小鼠中的集落促进活性及其靶标“前CFUc”
Colony promoting activity and its target 'pre-CFUc' in genetically anemic mice of W/Wv genotype.
作者信息
Miyanomae T, Tsurusawa M, Izumi H, Aizawa S, Mori K J, Kitamura Y
出版信息
Experientia. 1983 Jul 15;39(7):776-7. doi: 10.1007/BF01990322.
PMID:6602717
Abstract
Incubation of bone marrow cells with supernatant from long-term cultures of bone marrow cells increases the number of granulocyte-macrophage progenitor cells. This study reveals the presence of target cells of the colony promoting activity (CPA) in W/Wv mouse marrow. It is also shown that CPA does not stimulate erythroid colony formation in vitro.
摘要
将骨髓细胞与骨髓细胞长期培养的上清液共同孵育，可增加粒细胞-巨噬细胞祖细胞的数量。本研究揭示了W/Wv小鼠骨髓中存在集落促进活性（CPA）的靶细胞。研究还表明，CPA在体外不刺激红系集落形成。
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