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一项使用正电子发射断层扫描和氧-15吸入技术对部分性癫痫进行的发作间期研究。

An interictal study of partial epilepsy using positron emission tomography and the oxygen - 15 inhalation technique.

作者信息

Bernardi S, Trimble M R, Frackowiak R S, Wise R J, Jones T

出版信息

J Neurol Neurosurg Psychiatry. 1983 Jun;46(6):473-7. doi: 10.1136/jnnp.46.6.473.

Abstract

Data from ten patients with complex partial seizures who underwent positron emission tomography using the 15-0 inhalation technique are presented. Decreased flow and metabolism are noted in the hemisphere ipsilateral to the EEG focus, but, in patients with unilateral foci, bilateral changes in temporal cortex are detected. Other areas maximally affected include the basal ganglia, and the cerebellum. The possible role of anticonvulsant drugs in these findings is discussed.

摘要

本文呈现了10例复杂性部分性发作患者的数据,这些患者采用15-0吸入技术进行了正电子发射断层扫描。脑电图病灶同侧的大脑半球血流和代谢降低,但在单侧病灶患者中,颞叶皮质出现双侧变化。受影响最大的其他区域包括基底神经节和小脑。文中讨论了抗惊厥药物在这些发现中的可能作用。

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本文引用的文献

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Cerebral oxygen metabolism and blood flow in human cerebral ischemic infarction.
J Cereb Blood Flow Metab. 1982 Sep;2(3):321-35. doi: 10.1038/jcbfm.1982.33.
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Regional cerebral blood flow and EEG in patients with epilepsy.
Arch Neurol. 1978 Oct;35(10):648-57. doi: 10.1001/archneur.1978.00500340024005.

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