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用铊-201单光子发射断层扫描(SPETT)对犬梗死面积进行定量分析。

Quantification of infarct size in the dog by thallium-201 single photon emission transaxial tomography (SPETT).

作者信息

Maublant J, Gachon P, Moins N, Duchene-Marullaz P

出版信息

Eur Heart J. 1983 Apr;4(4):272-9. doi: 10.1093/oxfordjournals.eurheartj.a061459.

DOI:10.1093/oxfordjournals.eurheartj.a061459
PMID:6603975
Abstract

In a series of 12 dogs having an acute experimental anterior myocardial infarct, the size of the infarct was measured using, successively, single photon emission transaxial tomography (SPETT) with thallium-201, conventional planar scintigraphy of the anatomic slices, and planimetry of these slices after nitroblue-tetrazolium (NBT) staining. The tomographic views were obtained after processing of projection images collected during the rotation of a scintillation camera around the animals. A correlation of 0.86 was obtained between SPETT and NBT staining for the whole series, and a value of 0.94 was observed when only the transmural infarcts were considered. These results suggest that SPETT of the myocardium labelled with thallium-201 should allow a reliable, rapid and atraumatic estimation of the infarct size.

摘要

在一组12只患有急性实验性前壁心肌梗死的犬中,依次使用含铊-201的单光子发射断层扫描(SPETT)、解剖切片的传统平面闪烁显像以及这些切片经氯化硝基四氮唑蓝(NBT)染色后的平面测量法来测定梗死面积。断层图像是在闪烁相机围绕动物旋转过程中采集的投影图像经过处理后获得的。整个系列中,SPETT与NBT染色之间的相关性为0.86,仅考虑透壁性梗死时观察到的值为0.94。这些结果表明,用铊-201标记心肌的SPETT应能对梗死面积进行可靠、快速且无创的估计。

相似文献

1
Quantification of infarct size in the dog by thallium-201 single photon emission transaxial tomography (SPETT).用铊-201单光子发射断层扫描(SPETT)对犬梗死面积进行定量分析。
Eur Heart J. 1983 Apr;4(4):272-9. doi: 10.1093/oxfordjournals.eurheartj.a061459.
2
Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab.在犬实验中,使用单光子发射计算机断层扫描、铊-201和铟-111单克隆抗肌凝蛋白Fab片段测量梗死面积和心肌梗死百分比。
Circulation. 1987 Jul;76(1):181-90. doi: 10.1161/01.cir.76.1.181.
3
Quantification of myocardial infarct size by thallium-201 single-photon emission computed tomography: experimental validation in the dog.用铊-201单光子发射计算机断层扫描定量心肌梗死面积:犬实验验证
Circulation. 1986 Oct;74(4):852-61. doi: 10.1161/01.cir.74.4.852.
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Myocardial emission tomography with thallium-201. Value of multiple and orthogonal sections in the study of the myocardial infarction.铊-201心肌发射断层扫描。多层面及正交层面在心肌梗死研究中的价值。
Eur J Nucl Med. 1981;6(7):289-94. doi: 10.1007/BF00262522.
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Myocardial infarction in rats: high-resolution single-photon emission tomographic imaging with a pinhole collimator.大鼠心肌梗死:使用针孔准直器的高分辨率单光子发射断层成像
Eur J Nucl Med. 1996 Aug;23(8):896-900. doi: 10.1007/BF01084362.
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A comparison between conventional scintigraphy and emission tomography with thallium-201 in the detection of myocardial infarction: concise communication.传统闪烁扫描术与铊-201发射断层扫描术在检测心肌梗死方面的比较:简要通讯
J Nucl Med. 1982 Mar;23(3):204-8.
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Improved detection of myocardial infarction by emission computed tomography with thallium-201. Relation to infarct size.用铊-201发射型计算机断层扫描改善心肌梗死的检测。与梗死面积的关系。
Br Heart J. 1984 Dec;52(6):621-7. doi: 10.1136/hrt.52.6.621.
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Quantification of thallium-201 scintigrams in acute myocardial infarction.急性心肌梗死中铊-201闪烁图的定量分析。
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Quantitation of myocardial infarct size from thallium-201 images: validation of a new approach in an experimental model.通过铊-201图像定量测定心肌梗死面积:一种新方法在实验模型中的验证
J Am Coll Cardiol. 1984 Apr;3(4):948-55. doi: 10.1016/s0735-1097(84)80353-8.
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Estimation of infarct size by myocardial emission computed tomography with thallium-201 and its relation to creatine kinase-MB release after myocardial infarction in man.用铊-201心肌发射计算机断层摄影术估计梗死面积及其与人类心肌梗死后肌酸激酶-MB释放的关系。
Circulation. 1982 Nov;66(5):994-1001. doi: 10.1161/01.cir.66.5.994.

引用本文的文献

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A semi-automated method for edge detection in the evaluation of left ventricular function using ECG-gated single-photon emission tomography.一种用于使用心电图门控单光子发射断层扫描评估左心室功能时进行边缘检测的半自动方法。
Eur J Nucl Med. 1994 Nov;21(11):1206-11. doi: 10.1007/BF00182354.
2
Single photon emission computed tomography of the heart: a functional image?心脏单光子发射计算机断层扫描:一种功能图像?
Int J Card Imaging. 1986;2(1):47-52. doi: 10.1007/BF01553936.
3
Lack of correlation after reperfusion between ventricular function and infarct size estimated by thallium single-photon emission computed tomography.
再灌注后心室功能与通过铊单光子发射计算机断层扫描估计的梗死面积之间缺乏相关性。
Int J Card Imaging. 1988;3(4):203-8. doi: 10.1007/BF01797718.