Yang K T, Chen H D
Department of Nuclear Medicine, Changhua Christian Hospital, Taiwan, Republic of China.
Eur J Nucl Med. 1994 Nov;21(11):1206-11. doi: 10.1007/BF00182354.
Thallium-201 gated single-photon emission tomography (GSPET) of myocardium was performed at rest in 18 patients. Images were reconstructed to obtain end-diastolic (ED) and end-systolic (ES) images. The endocardial and epicardial edges of the left ventricle (LV) for the ED and ES images were defined for the mid-ventricular images of the short-axis slices, using a semi-automated method. LV wall thickness was measured for ED and ES images at 10 degrees intervals. Mean LV thickness was derived as the mean of the LV thickness for the three mid-ventricular slices. The systolic thickening (ST) was derived as: mean LV thickness (ES)--mean LV thickness (ED). The systolic thickening ratio (STR) was defined as: ST/mean LV thickness (ED). LV cavity area was measured. The dilation ratio (DR) was defined as: [mean cavity area (ED)--mean cavity area (ES)]/mean cavity area (ED). LV ejection fraction (LVEF) was estimated using technetium-99m gated blood pool study. There was a linear correlation between LVEF and ST (r = 0.85), LVEF and STR (r = 0.77) and LVEF and DR (r = 0.81). There was a strong correlation (r = 0.85) between regional STR and regional percent count increase in 52 segments which did not have perfusion defects. As well as for the evaluation of myocardial perfusion, GSPET images can be of use for the assessment of LV function using an appropriate method for LV edge detection.
对18例患者在静息状态下进行了心肌铊-201门控单光子发射断层扫描（GSPET）。重建图像以获得舒张末期（ED）和收缩末期（ES）图像。使用半自动方法，针对短轴切片的心室中部图像，确定ED和ES图像的左心室（LV）心内膜和心外膜边缘。以10度间隔测量ED和ES图像的LV壁厚度。平均LV厚度作为三个心室中部切片的LV厚度平均值得出。收缩期增厚（ST）计算为：平均LV厚度（ES）-平均LV厚度（ED）。收缩期增厚率（STR）定义为：ST/平均LV厚度（ED）。测量LV腔面积。扩张率（DR）定义为：[平均腔面积（ED）-平均腔面积（ES）]/平均腔面积（ED）。使用锝-99m门控血池研究估算LV射血分数（LVEF）。LVEF与ST（r = 0.85）、LVEF与STR（r = 0.77）以及LVEF与DR（r = 0.81）之间存在线性相关性。在52个无灌注缺损的节段中，局部STR与局部计数增加百分比之间存在强相关性（r = 0.85）。除了用于评估心肌灌注外，GSPET图像还可通过使用适当的LV边缘检测方法来评估LV功能。
