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脑脊液中总肌酸激酶活性作为心脏直视手术期间脑损伤的指标。

Total creatine kinase activity in cerebrospinal fluid as an indicator of brain damage during open-heart surgery.

作者信息

Lundar T, Stokke O

出版信息

Scand J Thorac Cardiovasc Surg. 1983;17(2):157-61. doi: 10.3109/14017438309109881.

DOI:10.3109/14017438309109881
PMID:6604311
Abstract

In a selected series of 33 patients undergoing open-heart surgery, the creatine kinase (CK) activity in cerebrospinal fluid (CSF) was compared with the clinical results in regard to the central nervous system. The level of CK activity in CSF showed correlation with the degree of irreversible neuronal damage. Determination of CK in CSF may thus be of prognostic value in these patients. Caution is essential, however, in the setting of strict limits above which return to normal or acceptable quality of life is not to be expected.

摘要

在一组选定的33例接受心脏直视手术的患者中,将脑脊液(CSF)中的肌酸激酶(CK)活性与中枢神经系统的临床结果进行了比较。脑脊液中CK活性水平与不可逆神经元损伤程度相关。因此,测定脑脊液中的CK可能对这些患者具有预后价值。然而,必须谨慎设定严格的界限,超过此界限则无法期望恢复正常或可接受的生活质量。

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Total creatine kinase activity in cerebrospinal fluid as an indicator of brain damage during open-heart surgery.脑脊液中总肌酸激酶活性作为心脏直视手术期间脑损伤的指标。
Scand J Thorac Cardiovasc Surg. 1983;17(2):157-61. doi: 10.3109/14017438309109881.
2
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Mitochondrial and MB isoenzymes of creatine kinase in cerebrospinal fluid from patients with hypoxic-ischemic brain damage.缺氧缺血性脑损伤患者脑脊液中肌酸激酶的线粒体同工酶和MB同工酶
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Thorax. 1986 May;41(5):386-95. doi: 10.1136/thx.41.5.386.