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门脉高压分流术

Shunts for portal hypertension.

作者信息

Weese J L, Yale C E, Pellett J R, Mendenhall J T, Starling J R

出版信息

Am Surg. 1983 Jul;49(7):365-8.

PMID:6604475
Abstract

Eighty-nine patients underwent 95 portasystemic shunts for portal hypertension at our institutions between June 1963 and March 1981. Ninety-three shunts were performed for bleeding varices. Procedures that were performed included 11 Warren shunts, 29 Linton shunts, 28 interposition mesocaval shunts, 26 classic portacaval shunts, and one umbilical to saphenous vein shunt. Thirty-six shunts were performed in Child class A patients (5.5% operative mortality), 37 in Child class B (16.2% operative mortality), and 22 in Child class c patients (36.3% operative mortality). Five-year survival for Child A patients was 74 per cent, 17.4 per cent for Child B patients and 26.3 per cent for Child C patients. Twelve of 14 patients (15.7%) who had recurrent postoperative upper gastrointestinal bleeding were found to have occluded shunts (two Warren, six Linton, one mesocaval, and three portacaval). Of 21 patients who became encephalopathic postoperatively, 17 had alcoholic liver disease. In 15 of these alcoholic patients who survived the immediate postoperative period, encephalopathy correlated directly with continued alcohol consumption. Several conclusions can be drawn from our data: portasystemic shunts can be performed with acceptable morbidity and mortality; rebleeding generally indicates shunt occlusion; encephalopathy can be correlated with continued alcohol consumption after shunting; there appears to be little difference in survival and rebleeding in the various shunt procedures; the poor survival figures for Child B and C patients must make one seriously consider alternative procedures in these poor-risk candidates.

摘要

1963年6月至1981年3月期间,我院89例患者接受了95次门体分流术以治疗门静脉高压。其中93次分流术是针对静脉曲张破裂出血进行的。手术方式包括11例Warren分流术、29例Linton分流术、28例间置式肠系膜上腔静脉分流术、26例经典门腔静脉分流术以及1例脐静脉至大隐静脉分流术。Child A级患者接受了36次分流术(手术死亡率为5.5%),Child B级患者37次(手术死亡率为16.2%),Child C级患者22次(手术死亡率为36.3%)。Child A级患者的5年生存率为74%,Child B级患者为17.4%,Child C级患者为26.3%。术后复发性上消化道出血的14例患者中有12例(15.7%)被发现分流道闭塞(2例Warren分流、6例Linton分流、1例肠系膜上腔静脉分流和3例门腔静脉分流)。术后发生肝性脑病的21例患者中,17例有酒精性肝病。在术后急性期存活的15例酒精性肝病患者中,肝性脑病与持续饮酒直接相关。从我们的数据中可以得出几个结论:门体分流术可以在可接受的发病率和死亡率下进行;再出血通常表明分流道闭塞;肝性脑病与分流术后持续饮酒有关;各种分流手术在生存率和再出血方面似乎没有太大差异;Child B级和C级患者的低生存率必须促使人们认真考虑对这些高危患者采用替代手术。

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