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超氧化物歧化酶为虹鳟（Salmo gairdneri）视网膜中的高氧环境提供保护。

Superoxide dismutase provides protection against the hyperoxia in the retina of the rainbow trout (Salmo gairdneri).

作者信息

Desrochers P E, Hoffert J R

出版信息

Comp Biochem Physiol B. 1983;76(2):241-7. doi: 10.1016/0305-0491(83)90065-2.

DOI:10.1016/0305-0491(83)90065-2
PMID:6605834
Abstract

A modified hydroxylamine oxidation assay method coupled with a parallel line analysis to detect endogenous interfering substances, was used to determine superoxide dismutase (SOD). Retinal SOD activities in trout, frog and rat were compared. SOD activity in liver and brain tissues was also determined. Based on estimates of superoxide anion production there appears to be excess SOD protection in the rainbow trout retina, which could, at least in part, account for its resistance to oxygen toxicity.

摘要

采用一种改良的羟胺氧化测定法并结合平行线分析来检测内源性干扰物质，以此测定超氧化物歧化酶（SOD）。比较了鳟鱼、青蛙和大鼠视网膜中的SOD活性。还测定了肝脏和脑组织中的SOD活性。基于超氧阴离子产生量的估计，虹鳟鱼视网膜中似乎存在过量的SOD保护作用，这至少可以部分解释其对氧毒性的抗性。

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