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[辐射对非同源干细胞失活现象中细胞相互作用的影响。辐照后B淋巴细胞功能的变化]

[Effect of radiation on cell interactions in the phenomenon of non-syngeneic stem cell inactivation. Changes in B-lymphocyte function after irradiation].

作者信息

Petrov R V, Dozmorov I M, Lutsenko G V, Nikolaeva I S, Rudneva T B

出版信息

Radiobiologiia. 1983 Nov-Dec;23(6):761-4.

PMID:6606819
Abstract

A study was made of the changes in the mode of interaction between T- and B-lymphocytes of mouse lymph nodes with respect to the phenomenon of inactivation of non-syngeneic haemopoietic stem cells. It was shown that irradiation of B-lymphocytes with doses of 77.4--232.2 mC/kg changes their helper activity into a suppressor activity with regard to T-cell-killers having a low electrophoretic mobility.

摘要

针对非同基因造血干细胞失活现象,对小鼠淋巴结中T淋巴细胞和B淋巴细胞之间相互作用模式的变化进行了研究。结果表明,用77.4--232.2 mC/kg剂量照射B淋巴细胞后,它们对电泳迁移率较低的T细胞杀伤细胞的辅助活性转变为抑制活性。

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