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[长期暴露于氧化氚后小鼠淋巴细胞对非同源造血干细胞的失活作用]

[Inactivation of non-syngeneic hematopoietic stem cells by mouse lymphocytes after long-term exposure to tritium oxide].

作者信息

Kirillova E N, Muksinova K N

出版信息

Radiobiologiia. 1985 Mar-Apr;25(2):255-8.

PMID:3889993
Abstract

A study was made of functional activity of lymphocytes, which inactivated nonsyngeneic colony-forming units (CFU) in allogenous and xenogenous interaction systems, at different times after long-term action of tritium oxide in a cumulative dose of approximately 9 Gy. The function of these lymphocytes was depressed during the first months after termination of exposure while at later times it exceeded the control level. The consequences of the interaction between lymphocytes and nonsyngeneic CFU were also studied in this work.

摘要

对在累积剂量约为9 Gy的氧化氚长期作用后的不同时间,在同种异体和异种相互作用系统中使非同种基因集落形成单位(CFU)失活的淋巴细胞的功能活性进行了研究。在接触终止后的最初几个月里,这些淋巴细胞的功能受到抑制,而在随后的时间里,其功能超过了对照水平。在这项工作中还研究了淋巴细胞与非同种基因CFU之间相互作用的后果。

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