偏钒酸铵对大鼠肝脏酶的影响。
Effects of ammonium metavanadate on rat liver enzymes.
作者信息
Beyhl F E, Mayer D G
出版信息
Toxicol Lett. 1983 Oct-Nov;19(1-2):81-5. doi: 10.1016/0378-4274(83)90265-5.
PMID:6606866
Abstract
Five min after administration of a single, i.p. dose of ammonium metavanadate (5 mg/kg), in rats, liver enzyme activities were measured. Microsomal mixed-function oxidases (except for aminopyrine N-demethylase), glucose-6-phosphatase and alkaline phosphatase were inhibited but lactate, malate, and glycerophosphate dehydrogenases as well as microsomal NADPH2-dependent cytochrome c reductase were unchanged.
摘要
给大鼠腹腔注射单剂量偏钒酸铵（5毫克/千克）5分钟后，测量其肝脏酶活性。微粒体混合功能氧化酶（氨基比林N-脱甲基酶除外）、葡萄糖-6-磷酸酶和碱性磷酸酶受到抑制，但乳酸脱氢酶、苹果酸脱氢酶、甘油磷酸脱氢酶以及微粒体NADPH2依赖性细胞色素c还原酶未发生变化。
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