Adamian S Ia, Chubarian A A
Biofizika. 1977 Jan-Feb;22(1):82-5.
Uncouplers of oxidative phosphorylation--gramicidin D, tetrachloro-2-trifluoromethylbenzimidasole (TTFB) and carbonylcyanide-m-trichlorphenylhydrazone (CCCP)--reduced ATP concentration in muscle. An increase of the buffer capacity of solution was without effect on uncoupling action of TTFB and CCCP but increased that of gramicidin D. The results can be explained by a different mechanism of the transfer of ion carriers through the membrane. It has been shown that ATP is not directly concerned with the membrane potential.
氧化磷酸化解偶联剂——短杆菌肽D、四氯-2-三氟甲基苯并咪唑（TTFB）和羰基氰化物间氯苯腙（CCCP）——降低了肌肉中的ATP浓度。溶液缓冲能力的增加对TTFB和CCCP的解偶联作用没有影响，但增加了短杆菌肽D的解偶联作用。这些结果可以通过离子载体通过膜的不同转运机制来解释。已经表明，ATP与膜电位没有直接关系。
