Malhotra K K, Kakar P N, Pillay P, Pathak L R, Chuttani H K
J Trop Med Hyg. 1978 Jun;81(6):113-5.
A fatal case of meningo-encephalitis due to Amoeba naegleria is discussed. It was a problem for diagnosis because of its unusual presentation. The patient, a young pregnant female presented with pyrexia, severe headache, and photophobia. Anti-biotic therapy was started after a provisional diagnosis of acute pyogenic meningitis had been made. There was no response to antibiotic therapy. Facial nerve palsy and abnormal activity in the left centro-temporal region in the EEG was observed and suspicion of an intra-cranial space occupying lesion was entertained. Carotid angiography and ventriculography, however, showed no abnormality. Repeat cerebrospinal fluid examination revealed motile amoebae. The patient, however, died shortly afterwards. This case is documented for its atypical clinical presentation and therapeutic problems.
本文讨论了一例由耐格里阿米巴引起的致命性脑膜脑炎病例。因其不寻常的表现，该病例在诊断上存在困难。患者为一名年轻孕妇，表现为发热、严重头痛和畏光。在初步诊断为急性化脓性脑膜炎后开始了抗生素治疗。抗生素治疗无效。观察到面神经麻痹和脑电图显示左中央颞区活动异常，怀疑有颅内占位性病变。然而，颈动脉血管造影和脑室造影未显示异常。重复脑脊液检查发现有活动的阿米巴。然而，患者不久后死亡。该病例因其非典型的临床表现和治疗问题而被记录。
