Bartram C I, Thornton A
AJR Am J Roentgenol. 1984 Feb;142(2):305-8. doi: 10.2214/ajr.142.2.305.
The diagnosis of familial polyposis depends on there being more than 100 adenomatous polyps in the large bowel. The polyps are the result of intramucosal microadenomatous growth. The age at which this occurs varies, and in the early stages of polyp development relatively few larger polyps may be seen. The numbers and size of the polyps as seen on double-contrast barium enema were compared with the macroscopic findings on the resected specimens in 27 patients with proven polyposis. Of these patients, 23 (83%) were diagnosed when polyps were first found at sigmoidoscopy. Radiologically the predominant polyp size was more than 5 mm in only four cases, 2-5 mm in 22 (81%), and less than 2 mm in one. Of the 22 with predominately 2-5 mm polyps, eight had significant numbers of nodules smaller than 2 mm and three had considerable numbers of polyps larger than 5 mm. Eleven (41%) were thought to have fewer than 70 polyps. Pathologically the nodular pattern (less than 2 mm) predominated in 11 (41%) and 14 had polyps of 2-5 mm. More than 100 polyps were present in each case, with fewer than 500 polyps in eight. In the 11 patients thought radiologically to have fewer than 70 polyps, the nodular pattern predominated in nine. In the initial stages of polyp growth, the larger polyps are less numerous, and the background nodular pattern is a useful diagnostic feature of familial polyposis.
家族性腺瘤性息肉病的诊断取决于大肠内存在100多个腺瘤性息肉。这些息肉是黏膜内微腺瘤生长的结果。出现这种情况的年龄各不相同，在息肉发展的早期阶段，可能只能看到相对较少的较大息肉。对27例经证实患有息肉病的患者，将双重对比钡灌肠检查所见息肉的数量和大小与切除标本的宏观检查结果进行了比较。在这些患者中，23例（83%）是在乙状结肠镜检查首次发现息肉时被诊断出来的。从放射学角度看，只有4例息肉的主要大小超过5毫米，22例（81%）为2 - 5毫米，1例小于2毫米。在主要为2 - 5毫米息肉的22例患者中，8例有大量小于2毫米的小结节，3例有相当数量大于5毫米的息肉。11例（41%）被认为息肉少于70个。病理检查显示，11例（41%）以小结节型（小于2毫米）为主，14例有2 - 5毫米的息肉。每例均有超过100个息肉，8例少于500个息肉。在放射学上被认为息肉少于70个的11例患者中，9例以小结节型为主。在息肉生长的初始阶段，较大的息肉数量较少，而背景小结节型是家族性腺瘤性息肉病的一个有用诊断特征。
