Homma S, Iwata K, Kusama T, Nakajima Y
Jpn J Physiol. 1983;33(5):711-20. doi: 10.2170/jjphysiol.33.711.
Conduction velocity (CV) of an action potential recorded from a single muscle fiber of the frog was measured with a new method, unidimensional latency-topography, and electrical membrane constants were determined for the same muscle fiber. CV = 1.96 +/- 0.27 m/sec (n = 52) at about 20 degrees C. Temperature coefficient of CV: Q10 = 2.0. Electrical membrane constants in the same muscle fibers (n = 52): lambda = 3.25 +/- 0.83 mm, tau = 33.4 +/- 14.3 msec, Cm = 6.09 +/- 2.13 mu F/cm2, D = 129.4 +/- 28.9 micron (mean +/- S.D.). The CV decreased linearly with increment of time constant, tau, and membrane capacity per unit area, Cm. The space constant, lambda, and the fiber diameter of the muscle fiber, D, did not correlate with CV. It was concluded that the T-system, which contributes largely to membrane capacity, has a great influence on the CV.
采用一种新方法——一维潜伏期地形图法，测量了从青蛙单根肌纤维记录的动作电位的传导速度（CV），并测定了同一肌纤维的电膜常数。在约20℃时，CV = 1.96±0.27米/秒（n = 52）。CV的温度系数：Q10 = 2.0。同一肌纤维（n = 52）的电膜常数：λ = 3.25±0.83毫米，τ = 33.4±14.3毫秒，Cm = 6.09±2.13微法/平方厘米，D = 129.4±28.9微米（平均值±标准差）。CV随时间常数τ和单位面积膜电容Cm的增加呈线性下降。空间常数λ和肌纤维直径D与CV无关。得出的结论是，对膜电容有很大贡献的T系统对CV有很大影响。
